The UV radiation from the sun to suspend, is a risk factor
for the development of skin cancer.
This applies to the two most common types of skin cancer: basal cell carcinoma
and the Squamous, two forms of mostly well-light curable skin cancer, and for
the rare but very aggressive melanoma. A recent study by U.S. scientists,
however, can suspect that the relationship between UV radiation and skin cancer
is more complex than previously thought.
Recent research suggests that promotes responsible for sunburn UV-B radiation
pale skin cancer, melanoma is not (directly).
In one study, American researchers, the influence of the energy-rich UV-B
radiation on the genome investigated. Laboratory tests on their blood cells from
melanoma patients that enhances UV-B radiation, the risk for the formation of
pale skin, but not for the emergence of melanoma. The latter has initially
puzzled.
UV-B radiation can fractures to the
strands of DNA to cause skin cancer and so trigger. This connection the
researchers wanted to further illuminate. As part of a study they took blood
samples from 469 patients with melanoma skin cancer or pale and 329 cancer-free
patients. The blood samples were in the laboratory UV-B radiation and 24 hours
later, the number of DNA breaks in the cells measured.
The result: The genome of patients with pale skin reacted much more sensitive to
UV-B radiation than that of the melanoma patients and the control group. A high
number of DNA breaks was associated with an almost threefold increased risk for
skin cancer associated bright. The propensity for such DNA breaks is through
individual problems with the genome repair reinforced. The risk for skin cancer
bright rose by an increase in the experimental UV-B for Dose further. But the
researchers found the same relationship between DNA breaks and risk of
melanoma.
But the results are no reason for complacency: the emergence of melanoma will
also be promoted UV light, however, probably through other mechanisms. Even the
UV-A radiation damages the DNA, but apparently not as dramatically: It causes no
strand breaks, but mutations, ie chemical changes in the molecules, which over
time accumulate. Eventually, according to the researchers, the DNA is damaged so
that the cells degenerate and also the dreaded malignant melanoma can form. The
recommendation is therefore continue: Protect yourself as well as possible
before the sun!
Sep 29
This entry was posted on Monday, September 29th, 2008 at 5:19 pmand is filed under Skin Disease. You can follow any responses to this entry through the RSS 2.0 feed. Both comments and pings are currently closed.
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